Search results for "stearic acid"

showing 10 items of 31 documents

Mycobacterium avium subsp. paratuberculosis (Map) Fatty Acids Profile Is Strain-Dependent and Changes Upon Host Macrophages Infection

2017

Johne´s disease is a chronic granulomatous enteritis of ruminants caused by the intracellular bacterium Mycobacterium avium subsp. paratuberculosis (Map). We previously demonstrated that Map isolates from sheep persisted within host macrophages in lower CFUs than cattle isolates after 7 days of infection. In the current study, we hypothesize that these phenotypic differences between Map isolates may be driven be the fatty acids (FAs) present on the phosphadidyl-1-myo-inositol mannosides of the Map cell wall that mediate recognition by the mannose receptors of host macrophages. FAs modifications may influence Map´s envelope fluidity ultimately affecting pathogenicity. To test this hypothesis…

0301 basic medicineMicrobiology (medical)Mycobacterium avium subp. paratuberculosis030106 microbiologyImmunologyParatuberculosisTuberculostearic acidBiologyMicrobiologyfatty acidsMicrobiologyCell wall03 medical and health scienceschemistry.chemical_compoundlipid metabolismmedicineExtracellularMacrophageMap-host interactionOriginal ResearchIntracellular parasitemedicine.diseasebiology.organism_classificationmacrophages030104 developmental biologyInfectious DiseaseschemistryBacteriaMycobacteriumFrontiers in Cellular and Infection Microbiology
researchProduct

trans-C18: 1 Isomers in Cheeses Enriched in Unsaturated Fatty Acids and Manufactured with Different Milk Fat Globule Sizes

2008

International audience; Increasing the knowledge on dietary fat composition, mainly the minor components, will improve the nutritional value of foods and their labeling. In this study, we examined the trans-octadecenoic acid (C18:1) composition of Emmental cheeses enriched in unsaturated fatty acids (FA) and manufactured with milks produced by cows selected to produce small and large fat globules. The FA composition of the milks was not significantly (P > 0.05) different from the FA composition of the corresponding Emmental cheeses. Increasing the unsaturated FA content of the cheeses using dietary manipulations lead to an increase in the trans-C18:1 and changed their isomeric profiles. In …

030309 nutrition & dieteticsVaccenic acid03 medical and health scienceschemistry.chemical_compoundfoodCheeseDAIRY PRODUCTLipid dropletLactation[SDV.IDA]Life Sciences [q-bio]/Food engineeringmedicineAnimalsLactationFood scienceGlobules of fatfood.cheeseChemical compositionUnsaturated fatty acidGlycoproteins0303 health sciencesChemistryMILK FAT COMPOSITION0402 animal and dairy sciencefood and beveragesLipid Droplets04 agricultural and veterinary sciencesGeneral ChemistryTRANS-FATTY ACIDTrans Fatty AcidsAnimal Feed040201 dairy & animal scienceEmmental cheeseMilkmedicine.anatomical_structureEMMENTAL CHEESEFatty Acids UnsaturatedAnimal Nutritional Physiological PhenomenaCattleFemaleComposition (visual arts)lipids (amino acids peptides and proteins)GlycolipidsGeneral Agricultural and Biological SciencesStearic Acids
researchProduct

The influence of tin compounds on the dynamic properties of liposome membranes: A study using the ESR method

2005

AbstractThe influence of organic and inorganic compounds of tin on the dynamic properties of liposome membranes obtained in the process of dipalmitoylphosphatidylcholine (DPPC) sonication in distilled water was investigated. This was carried out by means of the spin ESR probe method. The probes were selected in such a way as to penetrate different areas of the membrane (a TEMPO probe, 5-DOXYL stearic acid, 16-DOXYL stearic acid). Four compounds of tin were chosen: three organic ones, (CH3)4Sn, (C2H5)4Sn and (C3H7)3SnCl, and one inorganic one, SnCl2. The investigated compounds were added to a liposome dispersion, which was prepared prior to that. The concentration of the admixture was change…

12-DipalmitoylphosphatidylcholineShort CommunicationSonicationTin compoundsInorganic chemistrychemistry.chemical_elementDPPC liposomesBiochemistrychemistry.chemical_compoundOrganometallic CompoundsMolecular BiologyESRchemistry.chemical_classificationLiposomeElectron Spin Resonance SpectroscopyMembranes ArtificialCell Biologyequipment and suppliesMembraneHydrocarbonchemistryBiochemistryDistilled waterMolecular ProbesDipalmitoylphosphatidylcholineLiposomesSpin LabelsStearic acidTinCellular and Molecular Biology Letters
researchProduct

Stereochemical features of the hydrolysis of 9,10-epoxystearic acid catalysed by plant and mammalian epoxide hydrolases

2002

cis-9,10-Epoxystearic acid was used as a tool to probe the active sites of epoxide hydrolases (EHs) of mammalian and plant origin. We have compared the stereochemical features of the hydrolysis of this substrate catalysed by soluble and membrane-bound rat liver EHs, by soluble EH (purified to apparent homogeneity) obtained from maize seedlings or celeriac roots, and by recombinant soybean EH expressed in yeast. Plant EHs were found to differ in their enantioselectivity, i.e. their ability to discriminate between the two enantiomers of 9,10-epoxystearic acid. For example, while the maize enzyme hydrated both enantiomers at the same rate, the EH from soybean exhibited very high enantioselecti…

1303 BiochemistryStereochemistryMolecular Sequence DataDiol10050 Institute of Pharmacology and Toxicology610 Medicine & healthPolymerase Chain ReactionBiochemistrySubstrate Specificity1307 Cell BiologyHydrolysischemistry.chemical_compound1312 Molecular BiologyAnimalsOrganic chemistryMolecular BiologyDNA PrimersEpoxide HydrolasesMammalschemistry.chemical_classificationBase SequencebiologyChemistryHydrolysisFatty acidActive siteStereoisomerismCell BiologyPlantsRecombinant ProteinsRatsKineticsLiverMicrosomal epoxide hydrolaseEpoxide Hydrolasesbiology.protein570 Life sciences; biologyStereoselectivitySoybeansEnantiomerStearic AcidsResearch Article
researchProduct

Euonymus maackii Rupr. Seed oil as a new potential non-edible feedstock for biodiesel

2019

Abstract In this study, Euonymus maackii Seed oil (EMSO) was exploited and evaluated for the first time as a new non-edible oil feedstock for preparation of biodiesel. The EMSO yield was 41.06 ± 2.68 wt%. The fatty acid compositions of EMSO involved palmitoleic acid (2.01%), palmitic acid (14.5%), stearic acid (3.1%), oleic acid (49.8%), linoleic acid (29.3%), 11-Eicosenoic acid (0.1%) and arachidic acid (0.07%). Microwave-assisted transesterification with methanol provided a high conversion yield in short duration under low temperature. The 2.0 wt% of catalyst amount, 10:1 of methanol/oil molar ratio, 40 min of reaction time and 60 °C of temperature were found to be the optimum process condi…

Biodiesel060102 archaeologyRenewable Energy Sustainability and the Environment020209 energyLinoleic acidEN 1421406 humanities and the arts02 engineering and technologyPalmitic acidchemistry.chemical_compoundOleic acidchemistryBiodiesel production0202 electrical engineering electronic engineering information engineeringPalmitoleic acid0601 history and archaeologyFood scienceStearic acidRenewable Energy
researchProduct

Liver oleic acid biogenesis is impaired during the prehypertensive period in the spontaneously hypertensive rat.

2003

In the present study, we have investigated the liver microsomal stearic acid delta9 desaturation, and the fatty acid composition of liver microsomal total lipids in 10- and 30-day-old spontaneously hypertensive rats (SHRs), compared to the normotensive Wistar Kyoto (WKY) control rats. So as to avoid any influence related to the diet, the composition of the milk being different in SHR and WKY strains, the pups were suckled by adoptive normotensive female Wistar. After weaning, the 30-day-old rats were fed a standard commercial diet and then killed. Our results show lower liver microsomal delta9 desaturase activities in the 10- and 30-day-old SHR versus the WKY of the same age. The fatty acid…

Blood GlucoseFatty Acid DesaturasesMalemedicine.medical_specialtyAgingClinical BiochemistryBiologyRats Inbred WKYchemistry.chemical_compoundSpontaneously hypertensive ratInternal medicineRats Inbred SHRmedicineWeaningAnimalsRats WistarBody WeightFatty AcidsLipid metabolismCell BiologyOrgan SizeRatsOleic acidEndocrinologyEicosanoidchemistryAnimals NewbornLiverHypertensionMicrosomeMicrosomes LiverStearic acidStearoyl-CoA DesaturaseHormoneOleic AcidProstaglandins, leukotrienes, and essential fatty acids
researchProduct

Liquid chromatography-Fourier transform infrared spectrometric determination of cholesterol in animal greases

1997

Abstract Stearic acid, cholesterol and cholesteryl palmitate have been separated in less than 14 min by liquid chromatography on a column (3.9 mm i.d.×150 mm) of Nova-Pack C 18 (5 μm) using chloroform–acetonitrile (45 : 55) as mobile phase pumped at 0.5 ml min −1 ; Fourier transform infrared (FTIR) spectrometry was employed for both, general detection at 2868 or 2855 cm −1 and selective detection at 3285 cm −1 for stearic acid and 3526 cm −1 for cholesterol. In all cases a baseline established at 3900 cm −1 , 9-point smoothing and chromatographic peak height measurements were used. The method has been validated by application to the determination of cholesterol in animal greases and fish oi…

ChromatographyChloroformCholesterolMass spectrometryBiochemistryAnalytical Chemistrychemistry.chemical_compoundsymbols.namesakeFourier transformchemistrysymbolsEnvironmental Chemistrylipids (amino acids peptides and proteins)Petroleum etherStearic acidFourier transform infrared spectroscopySpectroscopySaponificationAnalytica Chimica Acta
researchProduct

Chromium(VI) oxide oxidation of non-ethoxylated and ethoxylated alcohols for determination by electrospray ionization mass spectrometry

2010

A new derivatization procedure to increase the sensitivity of electrospray ionization mass spectrometry (ESI-MS) to non-ethoxylated and ethoxylated alcohols was investigated. The analytes were oxidized with chromium(VI) oxide and the resulting carboxylic and ethoxy-carboxylic acids were isolated by extraction with ethyl acetate; the extracts were alkalinized and infused into the ESI-MS system working in the negative-ion mode. The yields of the combined oxidation-extraction were ca. 100% for non-ethoxylated fatty alcohols dissolved in acetone and they decreased moderately in samples containing increasing amounts of water (e.g., a 75% yield was obtained with 50% water). Ethoxylated alcohols w…

ChromatographyEthylene oxideCetyl alcoholElectrospray ionizationOrganic ChemistryExtraction (chemistry)Ethyl acetateAnalytical Chemistrychemistry.chemical_compoundchemistryStearic acidDerivatizationSpectroscopyStearyl alcoholRapid Communications in Mass Spectrometry
researchProduct

Identification of lipid binders in old oil paintings by separation of 4-bromomethyl-7-methoxycoumarin derivatives of fatty acids by liquid chromatogr…

2005

A HPLC-fluorescence method for identification of drying oils from binding media or protective film used in pictorial works of art prior to conservation or restoration is proposed. Fluorescence derivatization of fatty acids released by hydrolysis of structural drying oils is studied. The derivatization reagent was 4-(bromomethyl)-7-methoxycoumarin with 18-crown-6 as catalyst. Mobile phase was programmed from methanol-water (90:10 v/v) to methanol-water (100:0 v/v) in 25 min. The excitation and emission wavelengths were 325 and 395 nm, respectively. Under these chromatographic conditions, coumarin derivatives of myristic, palmitic, oleic and stearic acids were satisfactorily resolved. The met…

Detection limitChromatographyOrganic ChemistryDrying oilGeneral MedicineReference StandardsBiochemistryHigh-performance liquid chromatographyLipidsAnalytical ChemistryPalmitic acidchemistry.chemical_compoundHydrolysisVegetable oilSpectrometry FluorescencechemistryPaintingsStearic acidUmbelliferonesDerivatizationChromatography High Pressure LiquidJournal of chromatography. A
researchProduct

Structural properties of magnesium stearate pseudopolymorphs: effect of temperature.

2003

A thorough review of the relevant literature reveals that the interaction between water vapour and magnesium stearate, in contrast to many other metal soaps, is not properly understood. The structural modifications associated with the up-take or loss of water of vegetable-derived commercial magnesium stearate powders exposed to humid air or vacuum at room temperature are investigated using standard powder X-ray diffractometry. It is found that in such conditions magnesium stearate reacts reversibly with the vapour phase with structural consequences very similar to the high temperature transition between the crystalline and rotator phases of other anhydrous metal soaps. When temperature is i…

DiffractionChemical PhenomenaChemistry PhysicalAnalytical chemistryPharmaceutical ScienceWaterMetalHeatingCrystallographychemistry.chemical_compoundLattice constantchemistryDrug StabilityX-Ray Diffractionvisual_artX-ray crystallographyAnhydrousvisual_art.visual_art_mediumTechnology PharmaceuticalMagnesium stearateHydratePowder diffractionStearic AcidsInternational journal of pharmaceutics
researchProduct